Image: Alyssa K. Hartmann

Alyssa K. Hartmann

Technical Advisor

New York

Phone: 1(212) 318-6833
Fax: 1(212) 319-4090


Alyssa Hartmann is a technical advisor in the litigation practice of Paul Hastings and is based in the New York office. Dr. Hartmann received a B.S. in Chemistry from Texas Tech University in 2015, and a Ph.D. in Chemistry from the University of Connecticut in 2020. Dr. Hartmann has conducted research in the areas of chemistry, biochemistry, and immunology.

Engagement & Publications


  • Gavitt, T. D.; Hartmann, A. K.; Sawant, S. S.; Mara, A. B.; Szczepanek, S. M.; Rouge, J. L. A GATA3-Targeting Nucleic Acid Nanocapsule for In Vivo Gene Regulation in Asthma. ACS Nano. 2021, 15,11192-11201
  • Arifuzzaman, M.; Hartmann, A. K.; Rouge, J. L. Tracking nucleic acid nanocapsule assembly, cellular uptake and disassembly using a novel fluorescently labeled surfactant. RSC Adv. 2020, 10, 42349-42353
  • Tolentino, M. N.; Hartmann, A. K.; Loe, D. T.; Rouge, J. L Controlled Release of Small Molecules and Proteins from DNA-Surfactant Stabilized Metal Organic Frameworks. Mater. Chem. B. 2020, 8, 5627-5635
  • Hartmann, A. K.; Gudipati, S.; Pettenuzzo, A.; Ronconi, L.; Rouge, J. L. Chimeric siRNA-DNA Surfactants for the Enhanced Delivery and Sustained Cytotoxicity of a Gold(III) Metallodrug. Bioconjugate Chem. 2020, 31, 1063-1069
  • Santiana, J. J.; Gudipati, S.; Hartmann, A. K.; Rouge, J. L. ‘Hybrid Nucleic Acid Nanocapsules for Targeted, Enzyme-Specific Drug Delivery and Intracellular Gene Regulation,’ in Sakurai, K. and Ilies, M. A. Targeted Nanosystems for Therapeutic Applications: New Concepts, Dynamic Properties, Efficiency, and Toxicity. American Chemical Society, 2019, 59-77
  • Hartmann, A. K.; Cairns-Gibson, D. F.; Santiana, J. J.; Tolentino, M.; Barber, H.M.; Rouge, J. L. Enzymatically ligated DNA-surfactants: Unmasking Hydrophobically Modified DNA for Intracellular Gene Regulation. ChemBioChem. 2018, 19, 1734-1739
  • Awino, J. K.; Gudipati, S.; Hartmann, A. K.; Santiana, J. J.; Cairns-Gibson, D. F.; Gomez, N.; Rouge, J. L. Nucleic Acid Nanocapsules for Enzyme-Triggered Drug Release. Am. Chem. Soc. 2017, 139, 6278-6281
  • Zacharias, L. G.; Hartmann, A. K.; Song, E.; Zhao, J.; Zhu, R.; Mirzaei, P.; Mechref, Y. HILIC and ERLIC Enrichment of Glycopeptides Derived from Breast and Brain Cancer Cells. Proteome Res. 2016, 15, 3624-3634




University of Connecticut, Ph.D. 2020
Texas Tech University, B.S. 2015

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