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Isaac S. Ashkenazi

Partner, Litigation Department
T 1(212) 318-6432
F 1(212) 230-7892
Isaac S. Ashkenazi is a partner in the Litigation practice of Paul Hastings LLP. Mr. Ashkenazi focuses his practice on complex patent litigation primarily in the pharmaceutical, chemistry, and biotechnology fields. He has experience with a broad range of technologies, including pharmaceutical compounds, proteins, polymers, formulations, and chemical and synthetic processes. Mr. Ashkenazi has represented life sciences companies in patent cases involving a wide variety of therapeutics, including oncology drugs, proton pump inhibitors, sleep agents, respiratory agents, antiemetics, and cholesterol lowering and antidiabetic agents.


  • Secured a trial court victory for Helsinn Healthcare S.A. in a multi-defendant Hatch-Waxman litigation related to patents covering its injectable anti-emetic, Aloxi®
  • Successfully defended Sunovion Inc.’s patent covering its popular sleep aid, Lunesta® in one of the largest Hatch-Waxman Act litigations
  • Obtained favorable settlements on behalf of Allos Therapeutics, Inc. with multiple defendants seeking approval for generic versions of its Folotyn® cancer treatment
  • Representing Boehringer Ingelheim in connection with patent challenges relating to its proposed biosimilar version of Humira®, and in Hatch-Waxman litigations involving its blockbuster Pradaxa® stroke medication
  • Represented Amgen Inc. in a patent infringement case concerning a modified growth colony stimulating factor (G-CSF) for the treatment of neutropenia, and secured a complete walkaway in a patent infringement case brought by Teva concerning Amgen’s Sensipar® product used for the treatment of secondary hyperparathyroidism
  • Served as trial counsel for Pfizer Inc. (Wyeth) and Nycomed in a successful jury trial concerning a validity challenge to the patent covering the companies’ $2 billion-dollar-per-year acid-reflux medication, Protonix®

Professional and Community Involvement

  • Member of the State Bars of New York and New Jersey, and admitted to practice in the United States Court of Appeals for the Federal Circuit and the United States District Courts for the Southern District of New York and the District of New Jersey
  • Admitted to practice before the United States Patent and Trademark Office


  • Benjamin N. Cardozo School of Law, J.D. (concentration in Intellectual Property), 2005
  • The Cooper Union, B.E. in Chemical Engineering, 2002